Anti-Aging: Why We Are Getting Old?
Anti-Aging: Why We Are Getting Old?
We thought that aging is the result of our chronological age.
This chronological age doesn’t mean anything because aging is inside our cells and
especially in our DNA. It is the origin of aging.
Scientists have managed to define aging.
Why we are getting old? Aging is caused by 3 things:
DNA damage
Shortening of telomeres
Depletion of the stock of stem cells.
1 – DNA damage
We call it, progressive senescence because it settles down very slowly without been seeing because there are 200k-300k DNA damages per day.
The damage is of 2 types:
A – Due to the environment
Infections, UV rays, inadequate nutrition, pollution, heavy metals, tobacco, stress, and a sedentary lifestyle.
B – Due to internal attacks:
a – free radicals or oxidation
b – Inflammation which is due to cancers, diabetes, heart disease, insulin, cortisol, interleukin 6 (IL-6), TNFalpha, Alzheimer’s, auto-immune disease, obesity, bad eicosanoids.
c – Glycation: a lot of sugar in the body.
This advanced glycation will produce a lot of damage, blocking proteins that can no longer move and become paralyze by sugar that surrounds them, leading to aging and wrinkles.
Why we are getting old? and why is this important?
You know cells are dividing all the time. When the cell divides, the DNA divides, which is normal.
If the DNA is damaged, if the genetic codes are missing, the proteins will be missing and therefore we will have premature aging and chronic diseases.
Luckily we have, in the body, a maintenance service (DNA maintenance service) which is very sophisticated and will repair the damage.
2 – Shortening of telomeres
Telomere is the duplicative senescence, the aging of multiplication
Telomeres are the small caps that are found at the end of chromosomes and DNA to protect them against physical accidents.
They are repetitive sequences of DNA at the end of chromosomes.
The problem is that each time they divide, these telomeres get shorter but we always have the same sequence and the same codes. But after 5-6 divisions, there are no more telomeres or caps.
And, when a cell can no longer divide, it becomes senescent and this is why we are getting old.
3 – Depletion of the stock of stem cells
Stem cells are the fountain of youth.
The properties of stem cells:
a – make new cells
b – regenerate damaged tissues
c – to multiply
d – report (repair) with growth factors
From birth, the red marrow takes over for the production of hematopoietic (cells in the blood) and somatic stem cells.
A mother cell gives birth to 2 daughter cells with the same identity as the mother cell for the stem cells, one is the same and will remain available in the marrow as stock, the other called the generator cell will go into the blood.
Somatic cells are everywhere but not activated. They are ready to be used. They are all over the body.
When there is a signal sent by the marrow, it will make them and send to the blood.
The problem is that the stock of stem cells becomes depleted when the telomere gets shortened and that’s why we are getting old.
Everyone has the same wish:
To look young as long as possible
To think young: keep your memory intact, be able to remember a lot of things
To love young: have emotional relationships with others.
Creation of “Generation Young”
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It has the power to activate special genes, the survival genes to protect DNA.
2 – Products in capsules based on the research of telomeres.
It has been discovered that there is a gene, telomerase, which has the ability to repair the telomere when it is activated. But as the telomerase, in our body, is not activated for reasons which we do not know, we have found a product “the activator telomerase” (telomerase-65) which will activate it and which is included in this product.
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